Background：Spindle assembly factor. Required for normal assembly of mitotic spindles. Required for normal assembly of microtubules during apoptosis. Required for chromatin and/or kinetochore dependent microtubule nucleation. Mediates AURKA localization to spindle microtubules. Activates AURKA by promoting its autophosphorylation at 'Thr-288' and protects this residue against dephosphorylation.
仕様
Synonyms：C20ORF1,C20orf2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in lung cells 2,Differentially expressed in lung cells,DIL 2,DIL-2,DIL2,FLS353,GD：C20orf1,HCA 519,HCA519,HCTP 4,HCTP4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,p100,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,repp86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,TPX2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Fusion protein of human TPX2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
