Background：TPX2 （targeting protein for Xklp2） is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.
仕様
Synonyms：C20ORF1,C20orf2,Chromosome 20 Open Reading Frame 1,Differentially expressed in cancerous and non-cancerous lung cells 2,Differentially expressed in cancerous and noncancerous lung cells 2,Differentially expressed in lung cells 2,Differentially expressed in lung cells,DIL 2,DIL-2,DIL2,FLS353,GD：C20orf1,HCA 519,HCA519,HCTP 4,HCTP4,Hepatocellular carcinoma associated antigen 519,Hepatocellular carcinoma-associated antigen 519,p100,Preferentially expressed in colorectal cancer,Protein fls353,REPP 86,repp86,Restricted expression proliferation associated protein 100,Restricted expression proliferation-associated protein 100,Targeting protein for Xklp2,TPX 2,TPX2,TPX2 microtubule associated homolog,TPX2 microtubule associated protein homolog,TPX2 microtubule nucleation factor,TPX2
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.9mg/mL
Immunogen：Fusion protein of human TPX2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-2000, ELISA 1：2000-5000
Swissprot：Q9ULW0
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling
