Background：Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
仕様
Synonyms：GG2 1,Head and neck tumor and metastasis-related protein,MDC-3.13,NDED,NF-kappa-B-inducible DED-containing protein,SCC S2,SCC-S2,SCCS2,TFIP8,TNF alpha-induced protein 8,TNF induced protein,TNF-induced protein GG2-1,TNFAIP 8,TNFAIP8,Tumor necrosis factor alpha induced protein 8,Tumor necrosis factor alpha-induced protein 8
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Full length fusion protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-100, ELISA 1：2000-5000
Swissprot：O95379
Isotype：IgG
Research Areas：Cancer, Cell Biology, Immunology, Signal transduction
