Background：This gene encodes a multifunctional protein component of the heterogeneous nuclear ribonucleoprotein （hnRNP） complex. The hnRNP complex is involved in pre-mRNA splicing and the export of fully processed mRNA to the cytoplasm. This protein belongs to the FET family of RNA-binding proteins which have been implicated in cellular processes that include regulation of gene expression, maintenance of genomic integrity and mRNA/microRNA processing. Alternative splicing results in multiple transcript variants. Defects in this gene result in amyotrophic lateral sclerosis type 6.
仕様
Synonyms：75 kDa DNA pairing protein,75 kDa DNA-pairing protein,ALS6,Amyotrophic lateral sclerosis 6,fus,FUS CHOP,Fus like protein,FUS,FUS1,Fused in sarcoma,Fusion （involved in t（12;16） in malignant liposarcoma）,Fusion derived from t（12;16） malignant liposarcoma,Fusion gene in myxoid liposarcoma,Heterogeneous nuclear ribonucleoprotein P2,hnRNP P2,hnRNPP2,Oncogene FUS,Oncogene TLS,POMp75,RNA binding protein FUS,RNA-binding protein FUS,TLS,TLS CHOP,Translocated in liposarcoma,Translocated in liposarcoma protein
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.7mg/mL
Immunogen：Fusion protein of human FUS
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：30-150, ELISA 1：2000-10000
Swissprot：P35637
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Signal transduction
