Background:This gene encodes a nuclear serine/threonine kinase that was first identified in Arabidopsis. The encoded protein is thought to function in the regulation of chromatin assembly in the S phase of the cell cycle by regulating the levels of a histone H3/H4 chaperone. This protein is associated with double-strand break repair of DNA damage caused by radiation. Pseudogenes of this gene are present on chromosomes 10 and 17. Alternate splicing results in multiple transcript variants.
仕様
Synonyms:MGC44450,PKU alpha,PKU-alpha,Serine/threonine kinase,Serine/threonine protein kinase tousled like 2,Serine/threonine-protein kinase tousled-like 2,TLK 2,tlk2,TLK2,Tousled like kinase 2,Tousled-like kinase 2
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Fusion protein of human TLK2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-100, ELISA 1:2000-5000
Swissprot:Q86UE8
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling