Background:The protein encoded by this gene is a transketolase that acts as a homodimer and catalyzes the conversion of sedoheptulose 7-phosphate and D-glyceraldehyde 3-phosphate to D-ribose 5-phosphate and D-xylulose 5-phosphate. This reaction links the pentose phosphate pathway with the glycolytic pathway. Variations in this gene may be the cause of Wernicke-Korsakoff syndrome. Three transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:TK 2,TK2,TKR,TKT 2,TKT2,TKTL1,TKTL1,Transketolase 2,Transketolase like 1,Transketolase like protein 1,Transketolase related protein,transketolase-like 1,Transketolase-like protein 1,Transketolase-related protein,Transketolase2
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Fusion protein of human TKTL1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:30-150, ELISA 1:2000-10000
Swissprot:P51854
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction