Background：Syntaxin 12, also known as STX12, STX13 or STX14, is a 276 amino acid single-pass membrane protein that contains one t-SNARE coiled-coil homology domain and belongs to the Syntaxin family. Syntaxin 12 regulates protein transport between late endosomes and the trans-Golgi network and interacts with ABC1 （ATP-binding cassette transporter A1）, a protein that facilitates cellular release of choline-phospholipids and cholesterol to apoA-I （apolipoprotein A-I）.
