Background：This gene encodes a protein that is a member of the seven in absentia homolog （SIAH） family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized.
仕様
Synonyms：E3 ubiquitin-protein ligase SIAH1,FLJ08065,hSIAH1,HUMSIAH,Seven in absentia homolog 1 （Drosophila）,Seven in absentia homolog 1,Siah 1,Siah 1a,Siah E3 ubiquitin protein ligase 1,Siah-1,Siah-1a,Siah1,SIAH1,SIAH1A,Ubiquitin ligase SIAH1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Full length fusion protein
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
