Background:Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor whicHuman, Mouseay play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
仕様
Synonyms:KIAA1739,M-SEMA-F,S4c,SEM4C,Sema domain,immunoglobulin domain (Ig),transmembrane domain (TM) and short cytoplasmic domain,(semaphorin) 4C,SEMA4C,SEMACL1,SEMAF,SEMAI,Semaphorin-4C,UNQ5855/PRO34487
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Fusion protein of human SEMA4C
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-100, ELISA 1:2000-5000
Swissprot:Q9C0C4
Isotype:IgG
Research Areas:Cell Biology, Developmental biology, Neuroscience