Background:This protein belongs to the lipocalin family and is the specific carrier for retinol (vitamin A alcohol) in the blood. It delivers retinol from the liver stores to the peripheral tissues. In plasma, the RBP-retinol complex interacts with transthyretin which prevents its loss by filtration through the kidney glomeruli. A deficiency of vitamin A blocks secretion of the binding protein posttranslationally and results in defective delivery and supply to the epidermal cells.
仕様
Synonyms:OTTHUMP00000020114,OTTHUMP00000020115,OTTHUMP00000020116,Plasma retinol binding protein 4,Plasma retinol-binding protein,Plasma retinol-binding protein(1-176),PRBP,PRO2222,RBP,RBP4,RDCCAS,RET4,Retinol binding protein 4,Retinol binding protein 4 interstitial,Retinol binding protein 4 plasma
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.3mg/mL
Immunogen:Fusion protein of human RBP4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1000, ELISA 1:1000-2000
Swissprot:P02753
Isotype:IgG
Research Areas:Cancer, Cardiovascular, Metabolism, Signal transduction