Background：This gene encodes a ubiquitously expressed nuclear protein which belongs to a highly conserved subfamily of WD-repeat proteins. The encoded protein binds directly to retinoblastoma protein, which regulates cell proliferation. It interacts preferentially with the underphosphorylated retinoblastoma protein via the E1A-binding pocket B. Three alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.
仕様
Synonyms：RBBP 5,RBBP-5,RBBP5,RBBP5,RBQ 3,RBQ3,Retinoblastoma binding protein 5,Retinoblastoma binding protein RBQ3,Retinoblastoma binding protein5,Retinoblastoma-binding protein 5,Retinoblastoma-binding protein RBQ-3,SWD1,SWD1,Set1c WD40 repeat protein,homolog
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Fusion protein of human RBBP5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1000, ELISA 1：1000-2000
Swissprot：Q15291
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
