Background:This gene encodes a member of the M13 family, which includes type 2 integral membrane metallopeptidases. The encoded enzyme is a membrane-bound zinc-dependent metalloprotease. The enzyme catalyzes the cleavage of big endothelin to produce the vasoconstrictor endothelin-1, and plays a role in the processing of several neuroendocrine peptides. It may also have methyltransferase activity. Alternative splicing results in multiple transcript variants.
仕様
Synonyms:ECE 2,ECE-2,ECE2,ECE2,Endothelin converting enzyme 2,Endothelin-converting enzyme 2 region,Hypothetical protein MGC2408,KIAA0604,MGC17664,MGC78487
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Fusion protein of human ECE2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3