Background：VMP1 is a stress-induced protein that, when overexpressed, promotes formation of intracellular vacuoles followed by cell death. May be involved in the cytoplasmic vacuolization of acinar cells during the early stage of acute pancreatitis.VMP1 is a transmembrane protein that co-localizes with LC3, a marker of the autophagosomes. It interacts with beclin-1, a mammalian autophagy initiator, through the VMP1-Atg domain, which is essential for autophagosome formation.
仕様
Synonyms：DKFZP566I133,ectopic P-granules autophagy protein 3 homolog,NF E2 induceble protein 2,NF E2 inducible protein 2,ni 2,protein ni 2,Tango5,TDC1,TMEM49,Transmembrane protein 49,transport and golgi organization 5 homolog,Vacuole membrane protein 1,vmp1,VMP1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human VMP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
