Background：Cholesterol homeostasis is regulated, at least in part, by sterol regulatory element （SRE）-binding proteins （e.g., SREBP1; MIM 184756） and by liver X receptors （e.g., LXRA; MIM 602423）. Upon sterol depletion, LXRs are inactive and SREBPs are cleaved, after which they bind promoter SREs and activate genes involved in cholesterol biosynthesis and uptake.
仕様
Synonyms：MGC10327,StAR related lipid transfer protein 5,StAR-related lipid transfer （START） domain containing 5,StARD5,START domain containing 5,START domain containing protein 5
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,IHC,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human STARD5
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：40-1：150
Swissprot：Q9NSY2
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
