Background：The protein encoded by this gene is a member of the BAG1-related protein family. BAG1 is an anti-apoptotic protein that functions through interactions with a variety of cell apoptosis and growth related proteins including BCL-2, Raf-protein kinase, steroid hormone receptors, growth factor receptors and members of the heat shock protein 70 kDa family. This protein contains a BAG domain near the C-terminus, which could bind and inhibit the chaperone activity of Hsc70/Hsp70. This protein was found to be associated with the death domain of tumor necrosis factor receptor type 1 （TNF-R1） and death receptor-3 （DR3）, and thereby negatively regulates downstream cell death signaling.
仕様
Synonyms：BAG 4,BAG family molecular chaperone regulator 4,BAG-4,BAG4,BAG4,Bcl 2 associated athanogene 4,Bcl-2-associated athanogene 4,BCL2 associated athanogene 4,Silencer of death domains,SODD
Host：Rabbit
Reactivity：Human,Mouse
Applications：WB,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human BAG4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
