Background：SIK1 （salt-inducible kinase 1）, also known as SNF1LK or MSK, is a 783 amino acid protein that contains one UBA domain and one protein kinase domain and belongs to the Ser/Thr protein kinase family. Localized to both the nucleus and the cytoplasm, SIK1 uses magnesium as a cofactor to catalyze the ATP-dependent phosphorylation of target proteins and is thought to be important for the early stages of skeletal muscle growth and myocardial cell differentiation. Additionally, SIK1 has a potential role in regulation of the G2/M cell cycle transition, as well as in inhibitory control of CREB protein function.
仕様
Synonyms：KID2,MSK,myocardial SNF1 like kinase,QIK,Qin-induced kinase,Salt inducible kinase 1,Salt-inducible protein kinase 1,Serine threonine protein kinase SNF1 like kinase 1,Serine threonine protein kinase SNF1LK,Serine/threonine-protein kinase SIK1,Serine/threonine-protein kinase SNF1-like kinase 1,Serine/threonine-protein kinase SNF1LK,SIK-1,SIK1,SIK1,SNF1 like kinase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Synthetic peptide of human SIK1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：25-1：100
Swissprot：P57059
Isotype：IgG
Research Areas：Cancer, Cell Biology, Cardiovascular, Epigenetics and Nuclear Signaling, Signal transduction
