Background:SLC39A3 (solute carrier family 39, member 2), is a 314 amino acid acid multi-pass membrane protein that localizes to the cell membrane and belongs to the ZIP family of zinc transporters. Two isoforms of ZIP3 exist as a result of alternative splicing events. ZIP3 is involved in translocation of extracellular zinc into a variety of cell types. Tumorigenic prostate epithelial cells contain less intracellular zinc than non-tumorigenic prostate epithelial cells. Loss of the ability to maintain zinc accumulation may be caused by the decrease in the ZIP1 protein expression and the intracellular redistribution of ZIP3.
仕様
Synonyms:AI845814,MGC105842,MGC109671,MGC7461,S39A3,SLC,Slc39a3,Solute carrier family 39 (zinc transporter),member 3,Solute carrier family 39 member 3,Zinc transporter,Zinc transporter ZIP3,ZIP-3,Zip3,Zrt and Irt like protein 3,Zrt- and Irt-like protein 3
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human SLC39A3
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:Q9BRY0
Isotype:IgG
Research Areas:Cancer, Metabolism, Signal transduction