Background：Complex II of the respiratory chain, which is specifically involved in the oxidation of succinate, carries electrons from FADH to CoQ. The complex is composed of four nuclear-encoded subunits and is localized in the mitochondrial inner membrane. The iron-sulfur subunit is highly conserved and contains three cysteine-rich clusters which may comprise the iron-sulfur centers of the enzyme. Sporadic and familial mutations in this gene result in paragangliomas and pheochromocytoma, and support a link between mitochondrial dysfunction and tumorigenesis.
仕様
Synonyms：CWS2,DHSB,FLJ92337,Ip,Iron sulfur subunit,Iron sulfur subunit of complex II,Iron-sulfur subunit of complex II,mitochondrial,PGL 4,PGL4,SDH 1,SDH,SDH1,SDH2,SDH2,homolog of,SdhB,SDHIP,Succinate dehydrogenase [ubiquinone] iron sulfur protein mitochondrial,Succinate dehydrogenase [ubiquinone] iron sulfur subunit,Succinate dehydrogenase [ubiquinone] iron-sulfur subunit,succinate dehydrogenase [ubiquinone] iron-sulfur subunit,mitochondrial,Succinate Dehydrogenase 1 Iron Sulfur Subunit,Succinate Dehydrogenase 2,S. cerevisiae,homolog of,Succinate dehydrogenase complex iron sulfur subunit B,Succinate dehydrogenase complex subunit B iron sulfur,Succinate Dehydrogenase Complex Subunit B Iron Sulfur Protein,succinate dehydrogenase complex,subunit B,iron sulfur （Ip）,Succinate dehydrogenase iron sulfur protein
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human SDHB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：25-1：100
Swissprot：P21912
Isotype：IgG
Research Areas：Cancer, Cell Biology, Metabolism, Signal transduction
