Background:This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signaling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
仕様
Synonyms:90 kDa ribosomal protein S6 kinase 2,HU 2,KS6A2,MAP kinase activated protein kinase 1c,MAP kinase-activated protein kinase 1c,MAPK-activated protein kinase 1c,MAPKAP kinase 1c,MAPKAPK-1c,MAPKAPK1C,Mitogen.activated protein kinase-activated protein kinase 1C,p90 RSK3,p90-RSK 2,p90RSK2,pp90RSK3,Ribosomal protein S6 kinase alpha-2,ribosomal protein S6 kinase,90kDa,polypeptide 2,Ribosomal S6 kinase 3,RPS6KA2,RSK 3,RSK,RSK-3,S6K alpha,S6K alpha 2,S6K-alpha-2
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human RPS6KA2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:Q15349
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Signal transduction