Background:The protein encoded by this gene is a member of the NR1 subfamily of nuclear hormone receptors. It is a DNA-binding protein that can bind as a monomer or as a homodimer to hormone response elements upstream of several genes to enhance the expression of those genes. The encoded protein has been shown to interact with NM23-2, a nucleoside diphosphate kinase involved in organogenesis and differentiation, and to help regulate the expression of some genes involved in circadian rhythm.
仕様
Synonyms:bA133M9.1,NR1F2,Nuclear receptor ROR-beta,Nuclear receptor RZR beta,Nuclear receptor RZR-beta,Nuclear receptor subfamily 1 group F member 2,OTTHUMP00000021486,RAR related orphan receptor B,RAR related orphan receptor beta,Retinoic acid binding receptor beta,Retinoid-related orphan receptor-beta,ROR BETA,Rorb,RORB,RZR BETA,RZRB
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human RORB
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000, IHC 1:25-1:100
Swissprot:Q92753
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Neuroscience, Signal transduction