Background:This gene encodes a member of the Jumonji, AT-rich interactive domain 1 (JARID1) histone demethylase protein family. The encoded protein plays a role in gene regulation through the histone code by specifically demethylating lysine 4 of histone H3. The encoded protein interacts witHuman, Mouseany other proteins, including retinoblastoma protein, and is implicated in the transcriptional regulation of Hox genes and cytokines. This gene may play a role in tumor progression.
仕様
Synonyms:Histone demethylase JARID1A,JARID1A,Jumonji/ARID domain containing protein 1A,Jumonji/ARID domain-containing protein 1A,Kdm5a,KDM5A,Lysine-specific demethylase 5A,RBBP-2,RBBP2,RBP2,Retinoblastoma binding protein 2,Retinoblastoma-binding protein 2
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,IHC,ELISA
Concentration:1.2mg/mL
Immunogen:Synthetic peptide of human KDM5A
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:500-1:2000, IHC 1:50-1:300
Swissprot:P29375
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling