Background：The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3'-to-5' exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in the mitochondrial intermembrane space and is involved in import of RNA to mitochondria. Mutations in this gene have been associated with combined oxidative phosphorylation deficiency-13 and autosomal recessive nonsyndromic deafness-70. Related pseudogenes are found on chromosomes 3 and 7.
仕様
Synonyms：3' 5' RNA exonuclease,COXPD13,DFNB70,old-35,OLD35,PNPASE,PNPase 1,Polynucleotide phosphorylase like protein,Polyribonucleotide nucleotidyltransferase 1,mitochondrial
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.5mg/mL
Immunogen：Synthetic peptide of human PNPT1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：Q8TCS8
Isotype：IgG
Research Areas：Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism, Immunology
