Background：Phosphorylase kinase is a polymer of 16 subunits, four each of alpha, beta, gamma and delta. The alpha subunit includes the skeletal muscle and hepatic isoforms, and the skeletal muscle isoform is encoded by this gene. The beta subunit is the same in both the muscle and hepatic isoforms, and encoded by one gene. The gamma subunit also includes the skeletal muscle and hepatic isoforms, which are encoded by two different genes. The delta subunit is a calmodulin and can be encoded by three different genes. The gamma subunits contain the active site of the enzyme, whereas the alpha and beta subunits have regulatory functions controlled by phosphorylation.
仕様
Synonyms：5330411D17,9830108K24Rik,kinase PHKA1,KPB1,KPB1,MGC132604,Pcyt1b,PHKA,PHKA1,Phosphorylase b kinase regulatory subunit alpha,Phosphorylase b kinase regulatory subunit alpha,skeletal muscle isoform,Phosphorylase kinase alpha M subunit,phosphorylase kinase,alpha 1 （muscle）,RP23 210E20.1,skeletal muscle isoform
Host：Rabbit
Reactivity：Human,Rat
Applications：WB,IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human PHKA1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：25-1：100
Swissprot：P46020
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
