Background:The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE4 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
仕様
Synonyms:5''-cyclic phosphodiesterase 4A,cAMP specific phosphodiesterase,cAMP-specific 3'',cAMP-specific 3',5'-cyclic phosphodiesterase 4A,DPDE2,dunce like phosphodiesterase E2,PDE 4A,PDE4,PDE46,PDE4A,PDE4A,PDE4A11,Phosphodiesterase 4A,phosphodiesterase 4A cAMP specific,Phosphodiesterase 4A,cAMP-specific (dunce,phosphodiesterase E2 dunce homolog,Phosphodiesterase E2 dunce homolog,Drosophila,phosphodiesterase isozyme 4,phosphodiesterase type 4A11
Host:Rabbit
Reactivity:Human
Applications:WB,IHC,ELISA
Concentration:0.5mg/mL
Immunogen:Synthetic peptide of human PDE4A
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3