Background:This gene encodes a member of the protease-activated receptor (PAR) family which is a subfamily of the seven transmembrane G protein-coupled cell surface receptor family. The encoded protein acts as a cofactor in the thrombin-mediated cleavage and activation of the protease-activated receptor family member PAR4. The encoded protein plays an essential role in hemostasis and thrombosis. Alternate splicing results in multiple transcript variants that encode different isoforms.
仕様
Synonyms:coagulation factor II (thrombin) receptor-like 2,Coagulation factor II receptor-like 2,F2RL2,PAR 3,PAR-3,PAR3,PAR3,protease activated receptor 3,Proteinase-activated receptor 3,thrombin receptor like 2,Thrombin receptor-like 2
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.2mg/mL
Immunogen:Synthetic peptide of human F2RL2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:O00254
Isotype:IgG
Research Areas:Cardiovascular, Signal transduction