Background：This gene, CYP1A1, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by some polycyclic aromatic hydrocarbons （PAHs）, some of which are found in cigarette smoke. The enzyme's endogenous substrate is unknown; however, it is able to metabolize some PAHs to carcinogenic intermediates. The gene has been associated with lung cancer risk. A related family member, CYP1A2, is located approximately 25 kb away from CYP1A1 on chromosome 15.
仕様
Synonyms：AHH,AHRR,Aryl hydrocarbon hydroxylase,CP11,CP1A1,CYP 1,CYP1,cyp1a1,CYPIA1,Cytochrome P1 450 dioxin inducible,Cytochrome P1-450,Cytochrome P450 1A1,Cytochrome P450 family 1 subfamily A polypeptide 1,Cytochrome P450 form 6,Cytochrome P450 subfamily I （aromatic compound inducible） polypeptide 1,Cytochrome P450-C,Cytochrome P450-P1,Flavoprotein-linked monooxygenase,Microsomal monooxygenase,P1 450,P450 C,P450 form 6,P450 P1,P450DX,Xenobiotic monooxygenase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.3mg/mL
Immunogen：Synthetic peptide of human CYP1A1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：P04798
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Metabolism, Signal transduction
