Background：This is an N-ras oncogene encoding a membrane protein that shuttles between the Golgi apparatus and the plasma membrane. This shuttling is regulated through palmitoylation and depalmitoylation by the ZDHHC9-GOLGA7 complex. The encoded protein, which has intrinsic GTPase activity, is activated by a guanine nucleotide-exchange factor and inactivated by a GTPase activating protein. Mutations in this gene have been associated with somatic rectal cancer, follicular thyroid cancer, autoimmune lymphoproliferative syndrome, Noonan syndrome, and juvenile myelomonocytic leukemia.
仕様
Synonyms：ALPS4,AV095280,GTPase NRas,HRAS1,N ras,N ras protein part 4,Neuroblastoma RAS viral （v ras） oncogene homolog,NRAS,NRAS1,NS6,OTTHUMP00000013879,OTTMUSP00000023521,RASN,Transforming protein N Ras,Transforming protein N-Ras,v ras neuroblastoma RAS viral oncogene homolog
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：1.1mg/mL
Immunogen：Synthetic peptide of human NRAS
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
