Background：Members of the NALP protein family typically contain a NACHT domain, a NACHT-associated domain （NAD）, a C-terminal leucine-rich repeat （LRR） region, and an N-terminal pyrin domain （PYD）. The protein encoded by this gene belongs to the NALP protein family despite lacking the LRR region. This protein likely plays a regulatory role in the innate immune system. The protein belongs to the signal-induced multiprotein complex, the inflammasome, that activates the pro-inflammatory caspases, caspase-1 and caspase-5. Other experiments indicate that this gene acts as a multifunctional negative regulator of inflammation and apoptosis.
仕様
Synonyms：CLR11.1,NACHT,leucine rich repeat and PYD containing 10,NACHT,LRR and PYD domains containing protein 10,NACHT,LRR and PYD domains-containing protein 10,NAL10,NALP10,NLR family,pyrin domain containing 10,Nlrp10,NOD8,Nucleotide-binding oligomerization domain protein 8,Nucleotide-binding oligomerization domain,leucine rich repeat and pyrin domain containing 10,PAN5,PYNOD
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：1.2mg/mL
Immunogen：Synthetic peptide of human NLRP10
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
