Background：This gene is a member of the small GTPase superfamily and encodes a lipid-anchored, cell membrane protein with five repeats of the RAS-related GTP-binding region. This protein is vital in regulation of growth and cell cycle progression due to its role in the insulin/TOR/S6K signaling pathway. The protein has GTPase activity and shuttles between a GDP-bound form and a GTP-bound form, and farnesylation of the protein is required for this activity. Three pseudogenes have been mapped, two on chromosome 10 and one on chromosome 22.
仕様
Synonyms：Ras homolog enriched in brain 2,formerly,GTP binding protein Rheb,GTP-binding protein Rheb,MGC111559,Ras homolog enriched in brain 2,Ras homolog enriched in brain,RHEB 2,Rheb,RHEB,RHEB2,RHEB2,formerly
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,IHC,ELISA
Concentration：1.6mg/mL
Immunogen：Synthetic peptide of human RHEB
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000, IHC 1：50-1：200
Swissprot：Q15382
Isotype：IgG
Research Areas：Cancer, Metabolism, Signal transduction
