Background：The protein encoded by this gene binds arginine-vasopressin and may be involved in the arginine-vasopressin-mediated regulation of renal salt-water balance. The encoded protein also mediates inflammatory responses in the colon to allow recovery from intestinal epithelial damage and protects against tumorigenesis and the development of colitis. Finally, this protein can increase activation of NF-kappa-B, activation of CASP1 through interaction with ASC, and cAMP accumulation. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Angiotensin II/vasopressin receptor,AVR,CLR11.4,NACHT,leucine rich repeat and PYD containing 6,NACHT,LRR and PYD containing protein 6,NACHT,LRR and PYD domains-containing protein 6,NAVR,NAVR/AVR,NLR family,pyrin domain containing 6,Nlrp6,NLRP6,Nucleotide binding oligomerization domain,leucine rich repeat and pyrin domain containing 6,PAN3,PYPAF5,PYRIN containing APAF1 like protein 5,PYRIN-containing APAF1-like protein 5
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human NLRP6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P59044
Isotype：IgG
Research Areas：Cell Biology, Immunology, Signal transduction
