Background:The product of this gene is a member of the GCK group III family of kinases, which are a subset of the Ste20-like kinases. The encoded protein contains an amino-terminal kinase domain, and a carboxy-terminal regulatory domain that mediates homodimerization. The protein kinase localizes to the Golgi apparatus and is specifically activated by binding to the Golgi matrix protein GM130. It is also cleaved by caspase-3 in vitro, and may function in the apoptotic pathway. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined.
仕様
Synonyms:2610018G03Rik,EC 2.7.11.1,Mammalian Ste20 like protein kinase 4,Mammalian STE20-like protein kinase 4,Mammalian sterile 20 like 4,MASK,MST 4,MST-4,MST3 and SOK1 related kinase,Mst3 and SOK1-related kinase,Mst4,MST4,RGD1563568,RP23-245F8.1,RP6 213H19.1,Serine/threonine protein kinase 26,Serine/threonine protein kinase MASK,Serine/threonine protein kinase MST 4,Serine/threonine protein kinase MST4,Serine/threonine-protein kinase MASK,Serine/threonine-protein kinase MST4,STE20 like kinase MST 4,STE20 like kinase MST4,STE20-like kinase MST4,STK26
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:1mg/mL
Immunogen:Synthetic peptide of human MST4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:Q9P289
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction