Background:MOB1 was first identified in yeast as a protein that binds to Mps with essential roles in the completion of mitosis and the maintenance of ploidy. ItsDrosophilaand mammalian homologs, Mats and MOB1, respectively, are involved in the Hippo signaling tumor suppressor pathway, which plays a critical role in organ size regulation and which has been implicated in cancer development . There are two MOB1 proteins in humans, MOB1a and MOB1b, that are encoded by two different genes but which have greater than 95% amino acid sequence identity.
仕様
Synonyms:B1,Mps One Binder kinase activator like 1B (yeast),C2orf6,Chromosome 2 open reading frame 6,FLJ10788,FLJ11595,MATS1,MOB kinase activator 1A,MOB1,Mob1 alpha,Mob1 homolog 1B,MOB1 Mps One Binder homolog A,MOB1 Mps One Binder kinase activator like 1B,Mob1A,MOB4B,Mob4B protein,MOBK1B,Mobkl1b,MOL1B,Mps one binder kinase activator like 1B,Mps one binder kinase activator-like 1B,Protein Mob4B
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human MOB1A
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3