Background:This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined.
仕様
Synonyms:Alpha CP4,LIP4,LYST interacting protein,PCBP4,poly(rC) binding protein 4,rCbinding protein 4,RNA binding protein MCG10
Host:Rabbit
Reactivity:Human,Mouse
Applications:WB,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human PCBP4
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:WB 1:200-1:1000
Swissprot:P57723
Isotype:IgG
Research Areas:Cell Biology, Epigenetics and Nuclear Signaling