Background:The melanoma-associated antigen (MAGE) family consists of a number of antigens recognized by cytotoxic T lymphocytes. The MAGE genes were initially isolated from different kinds of tumors and, based on their virtually exclusive tumor-specific expression in adult tissues, they have been used as targets for cancer immunotherapy. MAGE genes encode for tumor-rejection antigens that are expressed in tumors of different histologic types and in normal testis and placenta. MAGE-B18 (melanoma-associated antigen B18) is a 343 amino acid protein that contains one MAGE domain and may be involved in tumorigenesis. The gene encoding MAGE-B18 maps to human chromosome X, which contains nearly 153 million base pairs and houses over 1,000 genes.
仕様
Synonyms:B430216B18Rik,MAGBI,MAGE-B18 antigen,MAGEB18,MAGEB18 antigen,Melanoma antigen family B,18,Melanoma-associated antigen B18,MGC114496,RGD1560369,RP23-289C5.3
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Synthetic peptide of human MAGEB18
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3