Background：This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80％ sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. Two transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms：Cancer/testis antigen 1.11,cancer/testis antigen family 1,member 11,CT1.11,MAGE 11,MAGE 11 antigen,MAGE11,MAGEA 11,Melanoma antigen family A 11,Melanoma associated antigen 11,MGC10511
Host：Rabbit
Reactivity：Human
Applications：IHC,ELISA
Concentration：0.8mg/mL
Immunogen：Synthetic peptide of human MAGEA11
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：P43364
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal transduction
