Background:MACC1 is a key regulator of the hepatocyte growth factor (HGF; MIM 142409)-HGF receptor (HGFR, or MET; MIM 164860) pathway, which is involved in cellular growth, epithelial-mesenchymal transition, angiogenesis, cell motility, invasiveness, and metastasis. Expression of MACC1 in colon cancer (MIM 114500) specimens is an independent prognostic indicator for metastasis formation and metastasis-free survival
仕様
Synonyms:7A5,MACC1,MACC1,Metastasis associated in colon cancer 1,Metastasis-associated in colon cancer protein 1,OTTHUMP00000201891,Putative binding protein 7a5,SH3 domain-containing protein 7a5,SH3BP4L
Host:Rabbit
Reactivity:Human
Applications:IHC,ELISA
Concentration:0.4mg/mL
Immunogen:Synthetic peptide of human MACC1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:Q6ZN28
Isotype:IgG
Research Areas:Cancer, Epigenetics and Nuclear Signaling, Signal transduction