Background：This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to eacHuman, Mouseember of the family. Alternatively spliced transcript variants of this gene have been reported but their full-length nature has not been determined.
仕様
Synonyms：LOXL,Loxl3,LOXL3,Lysyl oxidase homolog 3,Lysyl oxidase like 3,Lysyl oxidase-like protein 3
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human LOXL3
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
