Background:The protein encoded by this gene is a small Rho GTPase and a candidate tumor suppressor. The encoded protein interacts with the cullin-3 protein, a ubiquitin E3 ligase necessary for mitotic cell division. This protein inhibits the growth and spread of some types of breast cancer. Three transcript variants encoding different isoforms have been found for this gene.
仕様
Synonyms:DBC 2,Deleted in breast cancer 2,Deleted in breast cancer 2 gene protein,p83,RHBT2,Rho related BTB domain containing 2,Rho related BTB domain containing protein 2,Rho-related BTB domain-containing protein 2,RHOBTB 2,Rhobtb2
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:IHC,ELISA
Concentration:0.7mg/mL
Immunogen:Synthetic peptide of human RHOBTB2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:25-1:100
Swissprot:Q9BYZ6
Isotype:IgG
Research Areas:Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Signal transduction