Background：This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is known to metabolize as many as 20％ of commonly prescribed drugs. Its substrates include debrisoquine, an adrenergic-blocking drug; sparteine and propafenone, both anti-arrythmic drugs; and amitryptiline, an anti-depressant.
仕様
Synonyms：CPD6,CYP2D,CYP2D6,CYP2D7AP,CYP2D7BP,CYP2D7P2,CYP2D8P2,CYP2DL1,CYPIID6,Cytochrome P450 DB1,Cytochrome P450 family 2 subfamily D member 6,Cytochrome P450 family 2 subfamily D polypeptide 6,Debrisoquine 4 hydroxylase,Flavoprotein linked monooxygenase,Microsomal monooxygenase,P450 DB1,P450C2D,P450DB1,Xenobiotic monooxygenase
Host：Rabbit
Reactivity：Human
Applications：WB,IHC,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human CYP2D6
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000, IHC 1：25-1：100
Swissprot：P10635
Isotype：IgG
Research Areas：Cardiovascular, Metabolism, Signal transduction
