Background：The protein encoded by this gene was identified on the basis of its interaction with MAP3K12/DLK, a protein kinase known to be involved in the induction of cell apoptosis. This gene product contains a leucine zipper, which is a characteristic motif of transcription factors, and was shown to exhibit strong transactivation activity when fused to Gal4 DNA binding domain. Overexpression of this gene interfered with MAP3K12 induced apoptosis.
仕様
Synonyms：AATF,AATF,Apoptosis antagonizing transcription factor ,Apoptosis-antagonizing transcription factor,BFR2,CHE 1,CHE1,DED,Protein AATF,Rb binding protein Che 1,Rb-binding protein Che-1
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：WB,ELISA
Concentration：0.9mg/mL
Immunogen：Synthetic peptide of human AATF
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q9NY61
Isotype：IgG
Research Areas：Cell Biology, Epigenetics and Nuclear Signaling
