Background：This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium：neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.
仕様
Synonyms：5 HTT,5 HTTLPR,5 hydroxytryptamine （serotonin） transporter,5 hydroxytryptamine transporter,5HT transporter,5HTT,hSERT,HTT,Na+/Cl- dependent serotonin transporter,OCD1,SC6A4,Serotonin transporter 1,SERT,SERT1,Slc6a4,Sodium dependent serotonin transporter,Sodium-dependent serotonin transporter,Solute carrier family 6 （neurotransmitter transporter） member 4,solute carrier family 6 （neurotransmitter transporter,serotonin）,member 4,Solute carrier family 6 member 4
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.6mg/mL
Immunogen：Synthetic peptide of human SLC6A4
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：P31645
Isotype：IgG
Research Areas：Cancer, Metabolism, Neuroscience, Signal transduction
