Background：Diacylglycerol kinases （DGKs） are regulators of the intracellular concentration of the second messenger diacylglycerol （DAG） and thus play a key role in cellular processes. Nine mammalian isotypes have been identified, which are encoded by separate genes. Mammalian DGK isozymes contain a conserved catalytic （kinase） domain and a cysteine-rich domain （CRD）. The protein encoded by this gene is a diacylglycerol kinase, beta isotype. Two alternatively spliced transcript variants have been found for this gene.
