Background：This gene belongs to the dimethylarginine dimethylaminohydrolase （DDAH） gene family. The encoded enzyme plays a role in nitric oxide generation by regulating cellular concentrations of methylarginines, which in turn inhibit nitric oxide synthase activity. Impairment of DDAH causes ADMA accumulation and a reduction in cGMP generation. DDAH II, the predominant DDAH isoform in endothelial cells, facilitates the induction of nitric oxide synthesis by all-trans-Retinoic acid （atRA）. DDAH proteins are highly expressed in colon, kidney, stomach and liver tissues.
仕様
Synonyms：DDAH,DDAH I,DDAH-1,DDAH1,DDAH1,DDAHI,Dimethylargininase 1,Dimethylargininase-1,Dimethylarginine dimethylaminohydrolase 1,N（G）,N（G）-dimethylarginine dimethylaminohydrolase 1,NG NG dimethylarginine dimethylaminohydrolase
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human DDAH1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：50-1：200
Swissprot：O94760
Isotype：IgG
Research Areas：Cancer, Cardiovascular, Neuroscience
