Background：This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 （signal transducer and activator of transcription-1）] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor （AR）. It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis.
仕様
Synonyms：AR interacting protein,DDXBP1,DEAD/H （Asp-Glu-Ala-Asp/His） box binding protein 1,DEAD/H box binding protein 1,DEAD/H box-binding protein 1,E3 SUMO-protein ligase PIAS1,GBP,Gu binding protein,Gu-binding protein,GU/RH-II,Pias1,PIAS1,Protein inhibitor of activated STAT protein 1,Protein inhibitor of activated STAT,1,RNA helicase II binding protein,RNA helicase II-binding protein,Zinc finger,MIZ-type containing 3,ZMIZ3
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human PIAS1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：500-1：2000
Swissprot：O75925
Isotype：IgG
Research Areas：Cancer, Epigenetics and Nuclear Signaling
