Background：Rex-1 （for reduced expression）, also designated zinc finger protein 42 （ZFP42）, is an acidic zinc finger protein. Rex-1 contains four repeats of the zinc finger nucleic acid-binding motif and a potential acidic activator domain, suggesting that it is a regulatory protein. Rex-1 localizes to the nucleus and is highly expressed in embryonic stem （ES） and undifferentiated murine F9 teratocarcinoma cells. At the transcriptional level, expression of Rex-1 is reduced when F9 cells are induced to differentiate by the addition of retinoic acid （RA）, and Rex-1 repression is enhanced by E1A. The Oct-3/4 transcription factor can either activate or repress the Rex-1 promoter, depending on the cellular environment, while Oct-6 can lower the expression of Rex-1.
仕様
Synonyms：hREX-1,Reduced Expression 1 Protein,Reduced expression protein 1,Rex-1,REX1,REX1 transcription factor,Zfp-42,Zfp42,ZFP42 zinc finger protein,ZFP42,Zinc finger protein 42 homolog,Zinc finger protein 754,ZNF754
Host：Rabbit
Reactivity：Human
Applications：WB,ELISA
Concentration：0.2mg/mL
Immunogen：Synthetic peptide of human ZFP42
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：WB 1：200-1：1000
Swissprot：Q96MM3
Isotype：IgG
Research Areas：Cancer, Developmental biology, Stem cells
