Background:ADP-ribosylation factors (ARFs) play an important role in intracellular vesicular trafficking. The protein encoded by this gene is involved in the activation of ARFs by accelerating replacement of bound GDP with GTP and is involved in Golgi transport. It contains a Sec7 domain, which may be responsible for its guanine-nucleotide exchange activity and also brefeldin A inhibition.
仕様
Synonyms:ADP ribosylation factor guanine nucleotide exchange factor 2 (brefeldin A inhibited),ADP ribosylation factor guanine nucleotide exchange factor 2,ARFGEF 2,ARFGEF2,ARFGEP2,BIG 2,BIG2,Brefeldin A inhibited 2,Brefeldin A inhibited GEP 2,Brefeldin A inhibited guanine nucleotide exchange protein 2,dJ1164I10.1,FLJ23723
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,IHC,ELISA
Concentration:0.6mg/mL
Immunogen:Synthetic peptide of human ARFGEF2
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3