Background:The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion.
仕様
Synonyms:Adapter protein X11 alpha,Adapter protein X11alpha,Amyloid beta A4 precursor protein-binding family A member 1,Apba1,APBA1,Mint 1,Mint-1,Neuron specific X11 protein,Neuron-specific X11 protein,Neuronal Munc18 1 interacting protein 1,Neuronal Munc18-1-interacting protein 1,UROP11,x11,X11alpha
Host:Rabbit
Reactivity:Human,Mouse,Rat
Applications:WB,ELISA
Concentration:0.2mg/mL
Immunogen:Synthetic peptide of human APBA1
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3