Background:This gene encodes a member of a family of proteins that are structurally related to snake venom disintegrins and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. Expression of this gene has been used as a maternal serum marker for pre-natal development. Alternative splicing results in multiple transcript variants encoding different isoforms. Shorter isoforms are secreted, while longer isoforms are membrane-bound form.
仕様
Synonyms:A disintegrin and metalloproteinase domain 12,ADA12,ADAM 12,ADAM metallopeptidase domain 12,ADAM12,CAR10,Disintegrin and metalloproteinase domain-containing protein 12,MCMP,MCMPMltna,Meltrin alpha,Meltrin-alpha,Metalloprotease disintegrin 12 transmembrane,MLTN,MLTNA,OTTHUMP00000046766
Host:Rabbit
Reactivity:Human,Mouse
Applications:IHC,ELISA
Concentration:0.3mg/mL
Immunogen:Synthetic peptide of human ADAM12
Purification Method:Affinity purification
Clonality:Polyclonal
Conjugation:Unconjugated
Buffer:PBS with 0.05% sodium azide, 50% glycerol, PH7.3
Dilution:IHC 1:50-1:200
Swissprot:O43184
Isotype:IgG
Research Areas:Cancer, Cell Biology, Signal transduction