Background：The protein encoded by this gene is a member of the flamingo subfamily, part of the cadherin superfamily. The flamingo subfamily consists of nonclassic-type cadherins; a subpopulation that does not interact with catenins. The flamingo cadherins are located at the plasma membrane and have nine cadherin domains, seven epidermal growth factor-like repeats and two laminin A G-type repeats in their ectodomain. They also have seven transmembrane domains, a characteristic unique to this subfamily. It is postulated that these proteins are receptors involved in contact-mediated communication, with cadherin domains acting as homophilic binding regions and the EGF-like domains involved in cell adhesion and receptor-ligand interactions. The specific function of this particular member has not been determined.
仕様
Synonyms：Cadherin EGF LAG seven pass G type receptor 2 flamingo Drosophila homolog,Cadherin EGF LAG seven-pass G-type receptor 2,Cadherin family member 10,CDHF10,CELR2,Celsr2,EGF like domain multiple 2,EGF-like protein 2,EGFL2,epidermal growth factor like 2,Epidermal growth factor-like protein 2,Flamingo homolog 3,Flamingo1,KIAA0279,MEGF3,Multiple EGF-like domains protein 3,Multiple epidermal growth factor-like domains 3,Multiple epidermal growth factor-like domains protein 3
Host：Rabbit
Reactivity：Human,Mouse,Rat
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human CELSR2
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：25-1：100
Swissprot：Q9HCU4
Isotype：IgG
Research Areas：Cancer, Neuroscience, Signal transduction
