Background：This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; epigenetic silencing of SFRP genes leads to deregulated activation of the Wnt-pathway which is associated with cancer. This gene may also be involved in determining the polarity of photoreceptor cells in the retina.
仕様
Synonyms：Frizzled related protein 1,FRP 1,FRP,FRP-1,FRP1,FrzA,SARP 2,SARP-2,SARP2,Secreted apoptosis related protein 2,Secreted apoptosis-related protein 2,Secreted frizzled related protein 1,Secreted frizzled related protein,Secreted frizzled-related protein 1,SFRP 1,sFRP-1,SFRP1,SFRP1
Host：Rabbit
Reactivity：Human,Mouse
Applications：IHC,ELISA
Concentration：0.4mg/mL
Immunogen：Synthetic peptide of human SFRP1
Purification Method：Affinity purification
Clonality：Polyclonal
Conjugation：Unconjugated
Buffer：PBS with 0.05％ sodium azide, 50％ glycerol, PH7.3
Dilution：IHC 1：100-1：300
Swissprot：Q8N474
Isotype：IgG
Research Areas：Cancer, Cell Biology, Developmental biology, Neuroscience, Stem cells
